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Minipress can intensify the effects of alcohol. Be careful of the amount you drink.
If Minipress is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important that you check with your doctor before combining Minipress with the following:

Beta blockers such as Inderal
Dextroamphetamine (Dexedrine)
Diuretics such as Dyazide
Ibuprofen (Motrin, Advil, others)
Other high blood pressure medications

When taken with other medicines, which reduce, blood pressure there be may be a large drop in blood pressure, particularly with the first dose of Minipress . This is most likely to occur in people taking beta-blockers such as atenolol, or calcium channel blockers such as nifedipine and verapamil.

Most important fact about Minipress
If you have high blood pressure, you must take Minipress regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Minipress; and you must continue taking it even if you are feeling well.
Minipress does not cure high blood pressure; it merely keeps it under control.

Special precautions if you are pregnant or breastfeeding
The effects of Minipress during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, notify your doctor immediately.

Minipress passes into breast milk and may affect a nursing baby. Do not take Minipress without first talking to your doctor if you are breast-feeding a baby.

Special warnings about Minipress
The first dose of Minipress may cause dizziness, light-headedness or fainting. For this reason you should take the first dose, and preferably each dose, just before retiring to bed at night. Take care when moving from lying down to sitting or standing, particularly if you wake up in the night, until you know how Minipress affects you. If you feel dizzy or light-headed at any time during treatment, sit or lie down until the symptoms pass.

Minipress is not recommended for children under 12 years of age.

Minipress is not recommended for people who have ever fainted after passing urine (micturition syncope).

Minipress is not recommended for people who have heart failure due to a mechanical obstruction of the heart, such as heart valve disease or blood clot in the lung (pulmonary embolism).

Minipress can cause low blood pressure, especially when you first start taking the medication. This can cause you to become faint, dizzy, or light-headed, particularly on standing up. You should avoid driving or any hazardous tasks where injury could occur for 24 hours after taking the first dose or after your dose has been increased. Dizziness, fainting, or light-headedness may also occur in hot weather, when exercising, or when standing for long periods of time. Ask your doctor what precautions you should take. Blood pressure should be checked frequently throughout treatment.

If you have heart failure, Minipress may become less effective over time. If this happens you may notice weight gain or swelling of the legs or ankles. If this occurs, inform your doctor as the dose of Minipress or other medicines you are taking may need to be altered.
Minipress should be used with caution in people with decreased kidney function, decreased liver function, elderly people, and individuals taking blood pressure lowering medication.
Why Minipress should not be prescribed?
Avoid Minipress if it, or similar drugs such as Cardura, Quinazolines and Hytrin, give you an allergic reaction.

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Minipress can be taken with or without food.

To avoid falling, take the first dose at bedtime. Minipress may cause dizziness. It is a good idea to take every dose at bedtime, if possible.

Use caution when you stand or sit up from a lying position, especially if you wake up during the night. Dizziness may occur when changing positions.

Do not stop taking Minipress suddenly even if you feel better. Stopping suddenly could cause your blood pressure to increase.

Minipress should be taken exactly as prescribed by your doctor even if your symptoms have disappeared. Try not to miss any doses. If Minipress is not taken regularly, your blood pressure will increase.

If you miss a Minipress dose
Take it as soon as you remember. If it is almost time for your next Minipress dose, skip the one you missed and go back to your regular schedule. Never take 2 Minipress doses at the same time.

Adults
Dosages of Minipress should be adjusted by your doctor according to your response. The usual starting dose of Minipress is 1 milligram, 2 or 3 times per day.

The doctor may slowly increase the amount of Minipress to as much as 20 milligrams per day, divided into smaller doses. The typical dose is 6 milligrams to 15 milligrams per day, divided into smaller doses. Although doses higher than 20 milligrams per day usually have no extra effect, some people may benefit from a daily dose of 40 milligrams, divided into smaller doses.

If Minipress is used with a diuretic or other high blood pressure drug, the dose can be reduced to 1 to 2 milligrams, 3 times a day.

Children
Safety and effectiveness of Minipress have not been established in children.

Minipress overdose
Minipress taken in excess can have serious consequences. If you suspect a Minipress overdose, seek medical treatment immediately.

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Minipress is in a class of drugs called alpha-adrenergic blockers.

Minipress is used to treat hypertension (high blood pressure). Minipress is effective used alone or with other high blood pressure medications such as diuretics or beta-blocking medications (drugs that ease heart contractions) such as Tenormin.

Minipress is also prescribed for the treatment of benign prostatic hyperplasia (BPH), an abnormal enlargement of the prostate gland.

Minipress causes the blood vessels (veins and arteries) to relax and expand, which allows blood to pass more easily through them.
Minipress contains the active ingredient prazosin hydrochloride, which is a type of medicine called an alpha-blocker. Minipress works by blocking alpha-receptors in certain areas of the body.

Alpha-receptors are present on the muscle in the walls of blood vessels. When these receptors are blocked by Minipress, the muscle relaxes, causing the blood vessels to widen. The result of this is a lowering of blood pressure and Minipress can therefore be used to treat high blood pressure.

Widening of the blood vessels also decreases the effort required by the heart to pump blood around the body, as there is less resistance. This can help treat heart failure, where the pumping action of the heart has become less effective.

Minipress can also be used to treat Raynauds disease, where the blood vessels of the hands become narrowed, resulting in cold, painful hands. Widening of the blood vessels increases the blood flow to the extremities and relieves this pain.

Alpha-receptors are also present on the muscle in the prostate gland. This gland is found only in men and lies at the top of the tube connecting the bladder to the outside (urethra). The prostate gland often enlarges with advancing age (benign prostatic hyperplasia) and can cause urinary symptoms such as poor flow of urine. By blocking the alpha-receptors, Minipress causes the muscle in the prostate to relax. This allows urine to flow freely past the prostate and relieves the urinary symptoms.